Table 1 Bacteriophages have been approved by FDA (US) for Generally Recognized as Safe (GRAS) substances

GRN number Year Target Product's content (Phage) Notifier
198 2006 L. monocytogenes P100 EBI Food Safety (Micreos)
218 2007 L. monocytogenes P100 EBI Food Safety (Micreos)
435 2013 Salmonella Six-phage cocktail Intralytix
468 2013 Salmonella FO1a and S16 Micreos
528 2014 L. monocytogenes Six-phage cocktail Intralytix
603 2016 Salmonella BP-63 and BP-42 Phagelux
672 2017 Shigella Five-phage cocktail Intralytix
724 2018 Shiga toxin-producing E. coli Six-phage cocktail FINK TEC GmbH
752 2018 Salmonella BP-63 and LVR16-A Phagelux
757 2018 E. coli 0157:H7 Two-phage cocktail Micreos
827 2019 E. coli three-phage cocktail OmniLytics
834 2019 Shiga toxin-producing E. coli 3-8 phage cocktail Intralytix
GRN: GRAS notice.