Article
장내미생물과 퇴행성 뇌질환의 상호작용 특성
오상남1, 김영훈1, 문용일2,*
Characteristics of Interactions between Gut Microbiota and Degenerative Brain Diseases
Sangnam Oh1, Younghoon Kim1, Yong Il Moon2,*
1Dept. of Animal Science and Institute of Milk Genomics, Chonbuk National University, Jeonju, Korea
2Dept. of Animal Source Foods, Woosuk University, Wanju, Korea
*Corresponding author : Yong Il Moon, Dept. of Animal Source Foods, Woosuk University, Wanju, Korea Tel: +82-63-290-1488, Fax: +82-63-291-9312 E-mail:
yimoon@woosuk.ac.kr
Copyright © Korean Society for Lactic Acid Bacteria. All rights reserved. This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Published Online: Jun 30, 2019
Abstract
Social needs are increasing due to the increase of degenerative brain diseases because of the aging society. The most common type of degenerative brain diseases is Alzheimer's disease and Parkinson's disease, which makes most of cases. New scientific challenges indicate that gut microbiota are directly associated with the progress of degenerative brain diseases through triggering metabolic diseases, modulating immune response, and changing diversity of microbial community. A high-valuable strategy is proposed for the management of these disorders and as an adjuvant for psychiatric treatment of degenerative brain diseases and other related metabolic diseases through modulation of the gut microbiota including probiotics.
Keywords: degenerative brain diseases; gut microbiota; probiotics; aging society